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Research implicates metals in TSEs

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    Research implicates metals in TSEs

    A quick note, on the BSE science:

    In the paper, "Spontaneous generation of
    mammalian prions" by Charles Weissmann, John
    Collinge et al. June 29, 2010 Researchers state:

    "The apparent spontaneous generation of prions
    from normal brain tissue could result if the metal
    surface, possibly with bound cofactors, catalyzed
    de novo formation of prions from normal cellular
    prion protein."

    In this study, the control which was healthy brain
    tissue homogenate, resulted in misfolded prion
    proteins and disease ONLY when the healthy brain
    tissue homogenate was EXPOSED AND ATTACHED
    TO STAINLESS STEEL.

    Researchers hypothesis that "... infectivity is
    generated de novo, perhaps by a mechanism in
    which seed formation is catalyzed by the steel
    surface."

    This paper is available on-line for free.

    These findings confirms the findings of Dr. Vitaly
    Vodyanoy of Auburn University, Alabama who
    discovered that the formation of prions, as well as
    other misfolded proteins, was conditional upon
    nano-sized metal clusters attaching to the proteins.
    He calls these clusters "proteon nucleating centers"
    (PNCs), and he names the misfolded protein
    clusters "proteons", a general term.

    www.techquisition.com/files/04_39_59_PNC-
    Misfolded-Proteins.pdf

    Without binding to the "man-made" stainless steel
    wire, the healthy brain tissue innoculant DID NOT
    induce disease in their special lab mice that over-
    express the prion protein, neither did exposure to
    the stainless steel wire by itself. Although, they did
    not state for how long the tiny brains were exposed
    to the untreated wire.

    What has been confirmed in this study is the fact
    that the Rocky Mountain Laboratory "strain" (RML)
    that is used in many prion studies... is a man-made
    strain which very likely contains metal nanoclusters
    that induce misfolded proteins and disease. We are
    not told, anywhere, how these man-made prions
    are manufactured.

    Spontaneous production of misfolded proteins
    capable of inducing disease when injected directly
    into the brains of tga20 mice (mice over-
    expressing the prion protein) is DEPENDENT upon
    the adhesion of certain METALs (in this case
    stainless steel, a metal alloy), and possibly other
    co-factors present in liquified brain material.

    Already some researchers have speculated that
    people with metal plates, pace-makers etc, in their
    bodies/or brains might be more susceptible to
    disease. Others have commented on the above
    study, stating more research on other metals
    should be done. I would add that those
    toxins/chemicals that damage the blood-brain
    barrier would contribute to the intoxication of the
    brain (like organophosphates, monosodium
    glutamate, aspartame). The blood-brain barrier
    does not fully develop for years following birth.


    Dr. Vodyanoy has several USA patents on the
    subject of metals nucleating misfolded proteins:

    20080262206 Method of Isolating Proteon
    Nucleation Centers from Blood and Other Biological
    Materials
    20070128642 Method of isolation and self-
    assembly of small protein particles from blood and
    other biological materials
    20070122799 Method of isolation and self-
    assembly of small protein particles from blood and
    other biological materials
    20050142611 Method of isolation and self-
    assembly of small protein particles from blood and
    other biological materials
    20040137523 Method of isolation and self-
    assembly of small protein particles from blood and
    other biological materials


    Mark Purdey wrote a paper on the subject of Dr.
    Vodyanoys findings, as well:
    www.purdeyenvironment.com/auburn.htm

    Auburn university research substantiates the
    hypothesis that metal microcrystal nucleators
    initiate the pathogenesis of TSEs. Purdey M. Med
    Hypotheses. 2006;66(1):197-9. Epub 2005 Oct 13.


    For the last few weeks, I have noticed the late Mark
    Purdey's website www.markpurdey.com has been
    shut-down (not accessible). The family has told me
    that they are keeping this website active, since
    Mark's book "Animal Pharm" is generating a lot of
    attention.

    Marks co-author and brother, Nigel, maintains the
    website www.purdeyenvironment.com as well.

    They were unaware that the one website was not
    accessible and are looking into why this happened,
    when it started and getting things working again.

    There is so much evidence that these TSEs and
    other neurodegenerative diseases are the result of
    toxicity induced by various metals binding to
    proteins in an inappropriate manner. It is
    imperative that the truth be known.

    #2
    The only time something ends is when people give up. Thanks for not giving up Kathy....

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